British Air Force Typhoon jets have conducted a mission with France's air force in a coordinated attack on an hidden munitions depot in Syrian territory used by the IS group, according to the UK's MoD.
The location, pinpointed through surveillance, was assessed as storing arms and explosives, the statement said, and was positioned in mountains just to the north of the ancient city of Palmyra in Syria's central region.
"Our fighter planes used Paveway IV guided bombs to hit a several access tunnels providing entry to the facility... preliminary assessments are that the objective was successfully hit," the MoD said.
There was no indication of any civilian casualties in the operation on Saturday evening and each participating jet made a safe return, the defence officials confirmed.
The Typhoon FGR4s were backed up by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced extremist governance over significant areas in Syria and Iraq until 2019.
"This action shows our UK leadership, and resolve to work closely with our partners, to stamp out any resurgence of IS and their violent and radical beliefs in the Middle East," UK Defence Secretary the minister remarked.
British military aircraft have performed surveillance missions over Syrian airspace to "deter any attempted comeback" of Islamic State subsequent to its military defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I extend gratitude to every member of our armed forces involved in this mission for their professionalism and their valour," Healey said. "They were part of thousands of British personnel deployed over the holidays. This mission, to eliminate terrorist threats who pose a risk to our security, highlights how UK forces are prepared to act, throughout the year, ensuring Britain's security domestically and strong abroad."
Last December, the US military executed what it called a "major assault" targeting Islamic State objectives in Syria, after an assault killed two American soldiers and a civilian interpreter in the Palmyra area.
The UN says Daesh still boasts an estimated 5,000 to 7,000 fighters in both countries.